| Chemical Specifications | |
|---|---|
| Product Name | Retatrutide |
| CAS Number | 2381089-83-2 |
| Molecular Formula | C223H343N46O70 |
| Molecular Weight | 4731.33 g/mol |
| Purity (HPLC) | ≥ 99.0% |
| Appearance | White Lyophilized Powder |
| Storage | Store at -20°C (Protect from light and moisture) |
What is Retatrutide?
Retatrutide (10-Vial Kits, 5mg – 60mg) represents the pinnacle of metabolic research as a first-in-class, single-molecule Triple Hormone Receptor Agonist. By uniquely targeting GIP, GLP-1, and Glucagon receptors simultaneously, it shatters the efficacy limits of previous dual-agonists. This highly advanced compound is the ultimate research tool for investigating extreme obesity, non-alcoholic fatty liver disease (NAFLD), and profound metabolic syndrome reversal in clinical models.
Key Features & Research Benefits
Triple Agonist Mechanism
The only compound engineered to activate GIP, GLP-1, and Glucagon receptors concurrently. This tridimensional approach provides an unprecedented, synergistic model for studying complete metabolic and systemic lipid regulation.
Unprecedented Weight Loss
Surpasses all existing single and dual-agonists in clinical research models. It drastically amplifies central satiety signaling while uniquely preventing the metabolic slowdown typically associated with reduced caloric intake.
Profound Liver Fat Clearance
A breakthrough for NAFLD research. The inclusion of the Glucagon receptor actively promotes the rapid metabolism and clearance of ectopic fat deposits within the liver, normalizing hepatic function in severe metabolic models.
Increased Energy Expenditure
Unlike traditional therapies that merely suppress appetite, the Glucagon agonism in Retatrutide directly stimulates lipolysis and increases resting energy expenditure (basal metabolic rate), accelerating adipose tissue reduction.
Advanced Glycemic & Lipid Control
Delivers extraordinary regulation of blood glucose (HbA1c) while comprehensively improving the lipid profile. It serves as a vital tool for studying the rapid reduction of circulating triglycerides and LDL cholesterol.
Verified High Purity (≥99.0%)
Synthesized via state-of-the-art SPPS and delivered as a sterile, lyophilized powder. This ensures maximum molecular stability and exceptional batch-to-batch consistency for highly sensitive cardiometabolic research.
How It Works
Retatrutide operates through a revolutionary “Triple Agonist” mechanism, acting simultaneously on the receptors for Glucose-dependent Insulinotropic Polypeptide (GIP), Glucagon-Like Peptide-1 (GLP-1), and Glucagon. In biological models, this single molecule orchestrates a massive, synergistic cascade of metabolic responses that far exceeds the capabilities of targeting one or two pathways.
The GLP-1 and GIP agonism works heavily on the central nervous system and the pancreas. It powerfully delays gastric emptying, amplifies satiety signals in the hypothalamus, and stimulates glucose-dependent insulin secretion. This combination drastically reduces caloric intake and normalizes blood glucose levels. Furthermore, GIP activation uniquely enhances insulin sensitivity in white adipose tissue.
The true breakthrough of Retatrutide lies in the addition of Glucagon receptor agonism. While GLP-1 and GIP reduce energy intake, the activation of the glucagon receptor directly increases energy expenditure. It stimulates lipid mobilization, driving the body to burn stored fat for energy. Most notably, this specific pathway exerts a profound effect on the liver, rapidly clearing ectopic lipid deposits and providing a powerful mechanism for researching the reversal of Non-Alcoholic Fatty Liver Disease (NAFLD).
By simultaneously suppressing appetite, optimizing insulin response, and actively burning stored hepatic and visceral fat, Retatrutide provides researchers with the most comprehensive and potent metabolic regulatory tool developed to date.
🧪 What’s In The Kit
- Active Peptide: Highly Purified Retatrutide
- Format: 10 x Multi-dose Research Vials
- State: Sterile, Lyophilized Powder
- Net Contents: As selected (5mg to 60mg options)
- Purity: ≥99.0% (HPLC)
👩🔬 Who Uses It
- Cardiometabolic Scientists
- Obesity & Weight Management Labs
- Hepatology Researchers (NAFLD/NASH)
- Endocrinology Specialists
- Advanced Clinical Trial Administrators
🔗 Best Paired With
- Sterile Bacteriostatic Water (BAC)
- Precision Laboratory Pipettes
- Calibrated Insulin Syringes
- Vial Storage Organizers (-20°C)
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